Gastric cancer with adenocarcinoma and yolk sac tumor components: A rare entity
نویسندگان
چکیده
Despite a sharp worldwide decline in the incidence and mortality due to gastric cancer during the second half of the 20th century, gastric cancer remains the world's second leading cause of cancer-related deaths. Variants of gastric cancer account for approximately 5% of all stomach carcinomas. Herein, we report on a rare case of combined germ cell tumor and adenocarcinoma that arose in the stomach of a 68-year-old woman with a high level of alpha-fetoprotein in the serum. Clinical and pathological findings are presented.
منابع مشابه
Gastric Adenocarcinoma with Yolk Sac Tumor Differentiation and Liver Metastasis of Yolk Sac Tumor Component
Gastric adenocarcinoma with yolk sac tumor (YST) differentiation has rarely been reported. We report a case of primary gastric adenocarcinoma with yolk sac tumor differentiation and liver metastases of the YST component in a 50-years-old patient. This was suspected due to high serum level of alpha fetoprotein in the presence of a gastric fundal tumor. Gastric carcinoma with yolk sac tumor compo...
متن کاملAlpha-Fetoprotein-Producing Nonmetastatic Gastric Adenocarcinoma: A Rare Entity
Alpha-fetoprotein (AFP) is a plasma protein that is produced by the liver and the yolk sac during fetal development. In adults, an elevation in this protein can be exclusive to specific malignancies such as hepatocellular carcinoma, yolk sac tumors, and metastatic disease to the liver. In the clinical setting, an elevated AFP level and a liver mass (masses) translate to a diagnosis of hepatocel...
متن کاملGastric Yolk Sac Tumor: A Case Report and Review of the Literature
Gastric yolk sac tumors are extremely rare and their prognosis is poor; most patients have widespread metastases at the time of diagnosis. The treatment of gastric yolk sac tumors consists of aggressive chemotherapy combined with radiotherapy and surgery. Here, we first report a case of gastric yolk sac tumor presenting as an early gastric cancer that was cured after a gastrectomy with lymphade...
متن کاملBilateral ovarian mixed epithelial adenocarcinoma in a postmenopausal woman with unilateral ovarian yolk sac tumor component.
Ovarian yolk sac tumors (YSTs) usually occur in the young women and have been rarely documented in perimenopausal and postmenopausal women. The different age distribution supposes their complex nomenclature and histogenesis. We report a case of bilateral ovarian epithelial carcinoma with right ovarian YST component in a postmenopausal woman. The patient was treated by surgery and adjuvant combi...
متن کاملOvarian yolk sac tumor coexisting with epithelial ovarian cancer: An aggressive rare entity
Yolk sac tumor (YST) is the second most common subtype of ovarian germ cell tumors. It usually occurs in the second and third decades of life and is rare in postmenopausal women. In postmenopausal women, YST is commonly an aggressive tumor and can present as a pure germ cell component or as a mixed component with other germ cell or epithelial components. The recognition of this histological sub...
متن کامل